Matsumoto helped the Tigers overcome a 29-25 halftime deficit, scoring 10 of her points at the free throw line.
The Tigers took control of the game with a 32-point outburst in the fourth quarter.
Brianna Bishop led La Verne with 17 points and Karli Kato added 15.
Season Impact: The Tigers move to 7-6 overall and 3-1 in SCIAC play. Oxy has already beaten defending SCIAC champion Claremont-Mudd-Scripps so far this season.
La Verne falls to 0-12 overall and 0-3 in SCIAC.
Next Game: The Tigers are back in action at Whittier on Wednesday at 7 p.m.Follow Oxy Athletics on Twitter Sign Up for Newsletters Watch on Youtube Follow us on Instagram